Table 1

Genotyped SNPs associated with STAAD (p<5×10−8) with variants within and flanking the FBN1 gene

Stages 1, 2 and 3 combined (1313 cases, 1500 controls)
SNPBPAlleleORp ValueQ
rs1051917746544486G1.62.6×10−110.80
rs477451746546582A1.53.8×10−110.82
rs75525146599311G1.63.2×10−110.69
rs103647746702217G1.86.5×10−120.30
rs211818146703175G1.85.9×10−120.30
  • BP denotes NCBI Build 36.1 SNP physical position. Q denotes p value for the Cochran Q statistic for homogeneity between stages 1 and 2.6

  • SNP, single nucleotide polymorphism; STAAD, sporadic thoracic aortic aneurysm and dissection.