Baseline characteristics of the patients
| All patients (n=1074) | Patients with AMI (n=209) | Patients without AMI (n=969) | p Value* | Patients with STEMI (n=209) | Patients with non-STEMI (n=969) | p Value* | |
|---|---|---|---|---|---|---|---|
| Male, n (%) | 719 (67) | 151 (72) | 568 (66) | 0.069 | 31 (72) | 120 (72) | 0.98 |
| Age (years), median (IQR) | 64 (51–76) | 73 (61–80) | 62 (49–74) | <0.001 | 71 (53–78) | 73 (62–81) | 0.396 |
| Risk factors, n (%) | |||||||
| Hypertension | 683 (64) | 158 (76) | 525 (61) | <0.001 | 32 (77) | 125 (75) | 0.844 |
| Hypercholesterolemia | 480 (45) | 110 (53) | 370 (43) | 0.01 | 19 (44) | 91 (55) | 0.213 |
| Diabetes | 207 (19) | 75 (27) | 150 (17) | 0.001 | 10 (23) | 47 (28) | 0.454 |
| Current smoking | 254 (24) | 57 (27) | 197 (23) | 0.159 | 14 (33) | 43 (26) | 0.434 |
| History of smoking | 367 (34) | 72 (34) | 295 (34) | 0.893 | 10 (23) | 62 (37) | 0.067 |
| History, n (%) | |||||||
| History of coronary artery disease | 397 (37) | 100 (48) | 297 (34) | <0.001 | 14 (32) | 86 (52) | 0.024 |
| Previous myocardial infarction | 265 (25) | 71 (34) | 194 (22) | 0.001 | 10 (23) | 61 (37) | 0.096 |
| Peripheral artery disease | 73 (7) | 27 (13) | 46 (5) | <0.001 | 3 (7) | 24 (15) | 0.192 |
| Impaired kidney function | 110 (10) | 39 (19) | 71 (8) | <0.001 | 6 (14) | 33 (20) | 0.374 |
| Previous stroke | 61 (6) | 22 (11) | 39 (5) | 0.001 | 2 (5) | 20 (12) | 0.159 |
| All patients (n=1074) | Patients with AMI (n=209) | Patients without AMI (n=969) | p Value* | Patients with STEMI (n=43) | Patients with non-STEMI (n=969) | p Value* | |
| Vital parameters, median (IQR) | |||||||
| Heart rate (bpm) | 76 (66–90) | 81 (69–94) | 75 (66–90) | 0.089 | 82 (62–92) | 78 (69–89) | 0.721 |
| Systolic blood pressure (mm Hg) | 142 (127–159) | 140 (125–163) | 143 (128–159) | 0.614 | 137 (125–156) | 141 (124–164) | 0.545 |
| Diastolic blood pressure (mm Hg) | 84 (75–93) | 82 (73–93) | 84 (74–93) | 0.104 | 87 (78–97) | 81 (71–92) | 0.018 |
| ECG, n (%) | |||||||
| ST segment depression | 124 (12) | 68 (33) | 56 (7) | <0.001 | |||
| Abnormal Q-wave | 112 (10) | 29 (14) | 83 (10) | 0.069 | |||
| T-wave inversion | 143 (13) | 50 (24) | 93 (11) | <0.001 | |||
| Baseline values, median (IQR) | |||||||
| hs-cTnT† (µg/l) | 0.009 (0.004–0.024) | 0.091 (0.031–0.224) | 0.007 (0.003–0.013) | <0.001 | 0.136 (0.026–0.640) | 0.087 (0.032–0.188) | 0.237 |
| hFABP (ng/ml) | 2.7 (1.7–5.3) | 8.9 (4.2–24.2) | 2.3 (1.5–3.6) | <0.001 | 19.2 (8.4–61.7) | 8.0 (3.4–21.4) | <0.001 |
| Copeptin (mg/ml) | n=1063 | n=206 | n=857 | n=42 | n=164 | ||
| 6.7 (3.5–15.6) | 18.3 (7.1–45.3) | 5.7 (3.2–12.4) | <0.001 | 34.2 (16.9–110.8) | 13.6 (6.0–36.2) | <0.001 | |
*Continuous variables were compared with the use of the Mann–Whitney U test and categorical variables with the use of the Pearson's χ2 test.
†Roche high-sensitive troponin T.
AMI, acute myocardial infarction; hFABP, heart-type fatty acid-binding protein; non-STEMI, non-ST-elevation myocardial infarction; STEMI, ST-elevation myocardial infarction; non-ST-elevation myocardial infarction.