Table 2

Diagnostic performance of hFABP and cardiac troponin (95% CI)

Sensitivity, % (95% CI)Specificity, % (95% CI)Negative predictive value, % (95% CI)Positive predictive value, % (95% CI)
Heart type, FABP
ROC-derived optimal cut-off (4.2 ng/ml)
72 (65 to 89)80 (77 to 82)94 (92 to 95)41 (35 to 47)
Heart type, FABP
median (2.7 ng/ml)
87 (81 to 92)59 (56 to 63)96 (94 to 98)29 (25 to 33)
Roche high-sensitive troponin T
99th percentile (0.014 µg/l)
93 (88 to 96)77 (74 to 80)98 (97 to 99)42 (37 to 47)
Roche high-sensitive troponin T
≥0.014 µg/l
+ heart type, FABP
≥4.2 ng/ml
70 (63 to 77)89 (86 to 91)94 (92 to 96)55 (48 to 61)
Roche High-Sensitive troponin T
≥0.014 µg/l
+ heart type, FABP
≥2.7 ng/ml
83 (77 to 88)83 (80 to 85)96 (95 to 97)48 (42 to 54)
  • hFABP, heart-type fatty acid-binding protein; ROC, receiver operating characteristic.