Consistency analysis for small LVOTd 1.7–1.9 cm (mean 1.87±0.05)
| Less than severe AS by AVA | Severe AS by AVA | ||||
|---|---|---|---|---|---|
| Consistent grading AVA ≥cut-off MG ≤40 Vmax ≤4 | Inconsistent grading AVA ≥cut-off MG >40 Vmax >4 | Inconsistency | Consistent grading AVA <cut-off MG >40 Vmax >4 | Inconsistent grading AVA <cut-off MG ≤40 Vmax ≤4 | Inconsistency |
| AVA cut-off 1 cm2 | |||||
| n=268 | n=7 | Total inconsistency 3% | n=288 | n=269 | Total inconsistency 48% |
| SVI 50±9 (SVI ≤35=3%) | SVI 59±8* (SVI ≥58=57%) | (Inconsistency with SVI ≤58=1%) | SVI 43±9 | SVI 41±8* (SVI ≤35=21%) | (Inconsistency with SVI ≥35=38%) |
| AVA cut-off 0.9 cm2 | |||||
| n=370 | n=18 | Total inconsistency 5% | n=277 | n=167 | Total inconsistency 38% |
| SVI 48±9 (SVI ≤35=5%) | SVI 58±9* (SVI ≥58=56%) | (Inconsistency with SVI ≤58=2%) | SVI 43±9 | SVI 39±8* (SVI ≤35=27%) | (Inconsistency with SVI ≥35=28%) |
| AVA cut-off 0.8 cm2 | |||||
| n=447 | n=38 | Total inconsistency 8% | n=257 | n=90 | Total inconsistency 26% |
| SVI 47±9 (SVI ≤35=7%) | SVI 55±10* (SVI ≥58=37%) | (Inconsistency with SVI ≤58=5%) | SVI 42±8 | SVI 37±8* (SVI ≤35=37%) | (Inconsistency with SVI ≥35=16%) |
*p Value <0.02 compared with consistent grading SVI for each AVA cut-off.
AVA (cm2), MG (mm Hg), Vmax (m/s), SVI (ml/m2).
The ‘consistent grading’ and ‘inconsistent grading’ category columns contain the absolute number of patients assigned to that category, their stroke volume index and the percentage of patients with low flow (SVI ≤35 ml/m2) and high flow (SVI ≥58 ml/m2). The ‘inconsistency’ columns contain the total inconsistency and the remaining inconsistency with normal flow in parenthesis. All columns have been divided in three rows according to different AVA cut-offs for the small LVOTd group. The first row contains the patient category assignment under current guidelines. The second and third rows show the category reassignment of patients when cut-offs of 0.9 cm2 and 0.8 cm2 are used, respectively.
AS, aortic stenosis; AVA, aortic valve area; LVOTd, left ventricular outflow tract diameter; MG, mean gradient; SVI, stroke volume index.