Table 4

Consistency analysis for average LVOTd 2.0–2.2 cm (mean 2.11±0.08)

Less than severe AS by AVASevere AS by AVA
Consistent grading AVA ≥cut-off MG ≤40 Vmax ≤4Inconsistent grading AVA ≥cut-off MG >40 Vmax >4InconsistencyConsistent grading AVA <cut-off MG >40 Vmax >4Inconsistent grading AVA <cut-off MG ≤40 Vmax ≤4Inconsistency
AVA cut-off 1 cm2
n=2409n=151Total inconsistency 6% n=1554n=909Total inconsistency 37%
SVI 50±10 (SVI ≤35=4%)SVI 57±11* (SVI ≥58=42%)(Inconsistency with SVI ≤58=4%)SVI 46±8SVI 41±8* (SVI ≤35=23%)(Inconsistency with SVI ≥35=28%)
AVA cut-off 0.9 cm2
n=2844n=359Total inconsistency 11%n=1346n=474Total inconsistency 26%
SVI 49±10 (SVI ≤35=6%)SVI 54±10* (SVI ≥58=29%)(Inconsistency with SVI ≤58=8%)SVI 45±8SVI 39±7* (SVI ≤35=31%)(Inconsistency with SVI ≥35=18%)
AVA cut-off 0.8 cm2
n=3125n=750Total inconsistency 19%n=955n=193Total inconsistency 17%
SVI 48±10 (SVI ≤35=6%)SVI 51±9* (SVI ≥58=20%)(Inconsistency with SVI ≤58=15%)SVI 44±8SVI 37±7* n (SVI ≤35=40%)(Inconsistency with SVI ≥35=10%)
  • *p Value <0.0001 compared with consistent grading SVI for each AVA cut-off.

  • AVA (cm2), MG (mm Hg), Vmax (m/s), SVI (ml/m2).

  • The ‘consistent grading’ and ‘inconsistent grading’ category columns contain the absolute number of patients assigned to that category, their stroke volume index and the percentage of patients with low flow (SVI ≤35 ml/m2) and high flow (SVI ≥58 ml/m2). The ‘inconsistency’ columns contain the total inconsistency and the remaining inconsistency with normal flow in parenthesis. All columns have been divided in three rows according to different AVA cut-offs for the average LVOTd group. The first row contains the patient category assignment under current guidelines. The second and third rows show the category reassignment of patients when cut-offs of 0.9 cm2 and 0.8 cm2 are used, respectively.

  • AVA, aortic valve area; LVOTd, left ventricular outflow tract diameter; MG, mean gradient; SVI, stroke volume index.