Baseline characteristics of study groups
| Characteristics | Normal controls (n=33) | Moderate AS (n=63) | Severe asymptomatic AS (n=22) | Severe symptomatic AS (n=24) | p Value |
|---|---|---|---|---|---|
| Age, years | 62.4±7 | 67.5±13.0 | 68.3±19.2 | 69.8±10.3 | 0.12 |
| Male, n (%) | 21 (64) | 47 (75) | 13 (59) | 16 (67) | 0.49 |
| Body surface area, m2 | 1.86±0.21 | 1.98±0.19 | 1.86±0.22 | 1.88±0.19 | 0.05 |
| Time on treadmill, s | – | 1080±344 | 1042±350 | – | 0.69 |
| Diabetes, n (%) | – | 8 (13) | 0 (0) | 5 (21) | 0.09 |
| Current smokers, n (%) | – | 5 (8) | 3 (14) | 2 (8) | 0.72 |
| Antihypertensive treatment, n (%) | – | 10 (16)* | 4 (18)* | 14 (58) | <0.001 |
| Statin treatment, n (%) | – | 24 (38) | 13 (59) | 9 (38) | 0.19 |
Values are means±SD unless otherwise stated.
p<0.05 considered significant.
*Statistically significant difference from group with severe symptomatic AS.
AS, aortic stenosis.