Least square mean comparisons among LVOT groups at given cut-offs
| Group 1 (n=879) | Group 2 (n=5344) | Group 3 (n=3265) | p Value | p Value | Value | |
|---|---|---|---|---|---|---|
| Variable | LVOT 1.7–1.9cm | LVOT 2.0–2.2 cm | LVOT ≥2.3 cm | 1 vs 2 | 1 vs 3 | 2 vs 3 |
| AVA for Vmax=4 | 0.81 | 0.95 | 1.17 | <0.001 | <0.001 | <0.001 |
| AVA for Vmax=5 | 0.57 | 0.71 | 0.92 | <0.001 | <0.001 | <0.001 |
| AVA for AVAi=0.6 | 1.02 | 1.12 | 1.24 | <0.001 | <0.001 | <0.001 |
| AVAi for Vmax=4 | 0.49 | 0.51 | 0.57 | <0.001 | <0.001 | <0.001 |
| AVAi for Vmax=5 | 0.37 | 0.39 | 0.44 | <0.001 | <0.001 | <0.001 |
| Vmax for AVA=1 | 3.54 | 3.83 | 4.13 | <0.001 | <0.001 | <0.001 |
| Vmax for AVAi=0.6 | 3.52 | 3.59 | 3.72 | <0.001 | <0.001 | <0.001 |
| Vmax for MG=30 | 3.59 | 3.58 | 3.57 | 0.7 | 0.06 | 0.01 |
| Vmax for MG=40 | 4.11 | 4.1 | 4.09 | 0.7 | 0.06 | 0.01 |
| Vmax for MG=50 | 4.58 | 4.57 | 4.56 | 0.7 | 0.06 | 0.01 |
| MG for AVA=1 | 29 | 35 | 42 | <0.001 | <0.001 | <0.001 |
| MG for AVAi=0.6 | 28.8 | 30.3 | 33.1 | <0.001 | <0.001 | <0.001 |
| MG for Vmax=3 | 21 | 21.1 | 21.3 | 0.7 | 0.1 | 0.05 |
| MG for Vmax=4 | 37.3 | 37.3 | 37.5 | 0.7 | 0.1 | 0.05 |
| MG for Vmax=5 | 59 | 59.1 | 59.2 | 0.7 | 0.1 | 0.05 |
| DI TVI for AVA=1* | 0.36 | 0.29 | 0.22 | <0.001 | <0.001 | <0.001 |
| DI TVI for AVAi=0.6* | 0.36 | 0.32 | 0.28 | <0.001 | <0.001 | <0.001 |
| DI TVI for Vmax=4* | 0.3 | 0.28 | 0.25 | <0.001 | <0.001 | <0.001 |
*DI calculated by peak velocity was identical to DI TVI.
AVA (cm2), MG (mm Hg), Vmax (m/s), AVAi (cm2/m2).
AVA, aortic valve area; AVAi, indexed AVA; DI, dimensionless index; LVOTd, left ventricular outflow tract diameter; MG, mean gradient.