Echocardiographic and biohumoral changes from baseline to follow-up.
| Baseline (mean; SD) | FU (mean; SD) | Pairwise complete observations | Mean difference | p Value* | 95% CI | |
|---|---|---|---|---|---|---|
| LVEF | 0.48; 0.19 | 0.48; 0.16 | 77 | 0 | NS | −0.63 to 0.6 |
| LVEDV (ml) | 158; 92 | 137; 63 | 52 | 16 | 0.00022 | 7.9 to 24.0 |
| LVESV (ml) | 93; 84 | 85; 67 | 52 | 9 | 0.02 | 1.5 to 16.5 |
| EDVI (ml/m2) | 87; 48 | 79; 39 | 52 | 9 | 0.00028 | 4.4 to 13.6 |
| LVEDD (mm) | 58.6; 12.1 | 55.8; 11.1 | 41 | 1.6 | 0.03 | 0.1 to 3.1 |
| LVESD (mm) | 43.2; 15.8 | 41.4; 14.0 | 36 | 2.1 | 0.06 | −0.1 to 4.3 |
| LA diameter (mm) | 51; 11 | 49; 9 | 65 | 0 | NS | −1.63 to 1.6 |
| RV-RA gradient (mm Hg) | 47; 15 | 39; 15 | 62 | 7 | 0.0014 | 2.6 to 10.6 |
| nt-proBNP (ng/l) | 4474; 5885 | 2499; 3408 | 27 | 1126 | 0.03 | 98.5 to 2153.5 |
Data are given as mean±SD.
*p Value for between group comparisons of mean changes (only pairwise complete observations).
FU has been performed between 6 and 12 months after MitraClip implantation.
EDVI, end-diastolic volume index; LA, left atrium; LVEDD, left ventricular end-diastolic diameter; LVEDV, left ventricular end-diastolic volume; LVEF, left ventricular ejection fraction; LVESD, left ventricular end-systolic diameter; LVESV, left ventricular end-systolic volume: RA, right atrium; RV, right ventricle.