Multivariable Cox regression for outcomes
| Adjusted HR* (95% CI) | p Value | |
|---|---|---|
| Primary analysis | ||
| Inappropriate shocks (vs no inappropriate shocks) | 0.97 (0.70 to 1.36) | 0.873 |
| Appropriate therapy (vs no appropriate therapy) | 3.11 (2.41 to 4.02) | <0.001 |
| Both therapy types (vs no therapy) | 2.98 (1.95 to 4.56) | <0.001 |
| Secondary analysis | ||
| Inappropriate shocks (vs no therapy) | 1.05 (0.58 to 1.90) | 0.874 |
| Appropriate therapy (vs no therapy) | 3.16 (2.40 to 4.16) | <0.001 |
| Both therapy types (vs no therapy) | 2.98 (1.95 to 4.56) | <0.001 |
| Stratified analysis | ||
| LVEF ≤30% | ||
| Inappropriate shocks (vs no inappropriate shocks) | 0.79 (0.51 to 1.20) | 0.270 |
| Appropriate therapy (vs no appropriate therapy) | 2.93 (2.18 to 3.94) | <0.001 |
| LVEF >30% | ||
| Inappropriate shocks (vs no inappropriate shocks) | 1.56 (0.88 to 2.78) | 0.130 |
| Appropriate therapy (vs no appropriate therapy) | 3.55 (2.08 to 6.06) | <0.001 |
*Adjusted for age, gender, resynchronisation device, renal failure, atrial fibrillation, NYHA functional class, ejection fraction and β blocker usage.
LVEF, left ventricular ejection fraction (except in the stratified analysis); NYHA, New York Heart Association.