Table 2

Inflammatory response, indices of platelet activation and fibrinolytic function

PrePostp ValuePrePostp Value
Cellular response
 Neutrophils×109 cells/l7.7±0.67.2±±0.57.4±0.5*0.02
 Lymphocytes×109 cells/l2.0±0.11.9±±0.22.7±0.26*0.001
 Monocytes×109 cells/l0.7±0.10.6±±0.10.7±0.10.16
 Interleukin-6 (pg/ml)7.5±1.95.0±1.30.1310.6±4.05.8±2.0*0.01
 TNF-α (pg/ml)<0.1<0.1-0.12±0.02254±14*<0.0001
Platelet activation
 Platelet monocyte aggregates (%)27.7±4.933±5.80.2320.3±2.930.2±5.2*0.02
 Platelet surface P-selectin+ (%)6.7±0.56.5±0.70.766.2±1.35.0±0.70.15
Fibrinolytic function
 t-PA activity (IU/ml)0.45±0.140.45±±0.090.52±0.09*0.001
 PAI-1 activity (IU/ml)1.5 (0.8–2.7)0.9 (0.6–2.4)0.130.5 (0.4–0.9)1.1 (0.3–1.5)0.17
  • Data are expressed as the mean±SE or median (IQR) where appropriate. Statistical analyses compare 24 h with baseline using a paired t test or Mann–Whitney where appropriate.

  • *p<0.05.

  • PAI-1, plasminogen activator inhibitor type 1; TNF-α, tumour necrosis factor α.