Demographics and baseline characteristics of the study population
| Placebo n=73 | Niacin n=72 | p Value | |
|---|---|---|---|
| Age in years | 72 (69, 77) | 73 (69, 77) | 0.64 |
| Sex | |||
| Male (%) | 60 (82) | 58 (81) | 0.83 |
| Female (%) | 13 (18) | 14 (19) | |
| Race | |||
| Caucasian (%) | 65 (89) | 67 (93) | 0.74 |
| African–American (%) | 6 (8) | 3 (4) | |
| Other (%) | 2 (3) | 2 (3) | |
| Smoking (ever) (%) | 30 (42) | 27 (38) | 0.73 |
| Diabetes (%) | 16 (22) | 11 (15) | 0.39 |
| HbA1C % | 6 (5.8, 6.4) | 5.8 (5.6, 6.3) | 0.09 |
| Hypertension (%) | 53 (73) | 56 (78) | 0.57 |
| Prior MI (%) | 24 (33) | 22 (31) | 0.86 |
| Angina (%) | 37 (51) | 30 (42) | 0.32 |
| CABG (%) | 29 (41) | 21 (31) | 0.29 |
| PCI (%) | 36 (50) | 32 (47) | 0.74 |
| PVD (%) | 8 (11) | 7 (10) | >0.99 |
| Stroke (%) | 8 (11) | 13 (18) | 0.25 |
| Blood pressure | |||
| Systolic mm Hg | 134 (122, 146) | 128 (118, 140) | 0.06 |
| Diastolic mm Hg | 70 (64, 80) | 72 (64, 80) | 0.72 |
| Body Mass Index kg/m² | 28 (26, 35) | 28 (26, 33) | 0.41 |
| Abdominal circumference cm | 97 (91, 104) | 97 (89, 104) | 0.86 |
| Serum creatinine mmol/L | 76 (61, 84) | 72 (61, 84) | 0.81 |
Values in parentheses represent IQR or percentages, as appropriate. Differences tested using Wilcoxon rank-sum (continuous) or Fisher's exact (categorical) tests. MI denotes myocardial infarction. CABG denotes coronary artery bypass grafting. PVD denotes peripheral vascular disease.