Baseline characteristics of the general population and statin cohorts
| General population without CVD or diabetes | Statin users | |||
|---|---|---|---|---|
| Men (n=1890530) | Women (n=1917447) | Men (n=161377) | Women (n=139537) | |
| Age at index date | ||||
| Mean (sd) | 49.5 (11.5) | 50.7 (12.0) | 58.8 (9.3) | 61 (8.6) |
| Duration of follow-up | ||||
| Mean (sd) | 3.9 (4) | 4.2 (4.2) | 4 (3.1) | 4.3 (3.3) |
| Ethnicity | ||||
| White (%) | 606447 (32.1) | 733075 (38.2) | 71624 (44.4) | 65291 (46.8) |
| Black (%) | 19924 (1.1) | 23842 (1.2) | 873 (0.5) | 892 (0.6) |
| Indian (%) | 12034 (0.6) | 13196 (0.7) | 1146 (0.7) | 902 (0.6) |
| Other (%) | 26514 (1.4) | 32438 (1.7) | 1763 (1.1) | 1466 (1.1) |
| Unknown (%) | 1225611 (64.8) | 1114896 (58.1) | 85971 (53.3) | 70986 (50.9) |
| Body mass index | ||||
| Low (<20) (%) | 27309 (1.4) | 83477 (4.4) | 1314 (0.8) | 2930 (2.1) |
| Normal (≥20–<26) (%) | 379674 (20.1) | 570312 (29.7) | 34212 (21.2) | 35254 (25.3) |
| Overweight (≥26) (%) | 508803 (26.9) | 559330 (29.2) | 81066 (50.2) | 67591 (48.4) |
| Unknown (%) | 974744 (51.6) | 704328 (36.7) | 44785 (27.8) | 33762 (24.2) |
| Smoking status | ||||
| No (%) | 564673 (29.9) | 821574 (42.8) | 56895 (35.3) | 63491 (45.5) |
| Past (%) | 239755 (12.7) | 230404 (12.0) | 43588 (27.0) | 25103 (18.0) |
| Current (%) | 403422 (21.3) | 364550 (19.0) | 42204 (26.2) | 33034 (23.7) |
| Unknown (%) | 682680 (36.1) | 500919 (26.1) | 18690 (11.6) | 17909 (12.8) |
| Systolic blood pressure | ||||
| Recorded (%) | 1205152 (63.7) | 1565999 (81.7) | 156004 (96.7) | 136138 (97.6) |
| Mean (sd) | 132.6 (16.2) | 127.8 (18.0) | 141.9 (17.6) | 141.2 (18.7) |
| Cholesterol HDL ratio | ||||
| Recorded (%) | 336579 (17.8) | 353677 (18.4) | 123314 (76.4) | 104198 (74.7) |
| Mean (sd) | 4.4 (1.3) | 3.7 (1.2) | 5.3 (1.5) | 4.7 (1.4) |
| Cholesterol | ||||
| Recorded (%) | 462057 (24.4) | 484668 (25.3) | 146672 (90.9) | 126441 (90.6) |
| ≥6 mmol/l (%) | 125193 (27.1) | 150901 (31.1) | 94067 (64.1) | 101886 (80.6) |
| Number of GP records in year before | ||||
| Mean (sd) | 10.1 (15.2) | 16.3 (18.4) | 25.8 (18.5) | 32.1 (21.5) |
| Treated hypertension (%) | 155293 (8.2) | 191104 (10) | 71477 (44.3) | 65348 (46.8) |
| Atrial fibrillation (%) | 16275 (0.9) | 9742 (0.5) | 5170 (3.2) | 2751 (2.0) |
| Chronic renal disease (%) | 14729 (0.8) | 20943 (1.1) | 5173 (3.2) | 6323 (4.5) |
| Rheumatoid arthritis (%) | 8633 (0.5) | 21818 (1.1) | 1452 (0.9) | 3032 (2.2) |
| Left ventricular hypertrophy (%) | 5907 (0.3) | 3523 (0.2) | 2131 (1.3) | 1140 (0.8) |