Baseline characteristics and yearly aortic dilatation rate according to BAV subtype
| Typical, no raphe N=57 | Atypical, no raphe N=56 | Typical, with raphe N=204 | Atypical, with raphe N=29 | p Value | |
|---|---|---|---|---|---|
| Clinical characteristics | |||||
| Age, years | 43±15 | 46±15 | 50±14 | 48±15 | 0.004 |
| Male gender, n (%) | 41 (72%) | 34 (61%) | 155 (76%) | 20 (69%) | 0.15 |
| Echocardiographic characteristics | |||||
| Ejection fraction, % | 59.4±8 | 57.2±8 | 59.9 | 61.3 | 0.64 |
| AR≥moderate | 20 (35%) | 11 (20%) | 84 (41%) | 8 (28%) | 0.02* |
| AS≥moderate | 6 (12%) | 10 (20%) | 30 (16%) | 4 (15%) | 0.69 |
| Baseline aortic dimension | |||||
| Annulus | 25±3.6 | 25±3.5 | 25±2.9 | 25±1.9 | 0.77 |
| Valsalva sinuses | 37.7±5.7 | 34.7±5.7 | 38.1±5.4 | 34.1±3.3 | 0.0001* |
| Sinotubular junction | 31.1±5.2 | 31.1±5.2 | 32.2±5.3 | 29.1±3.6 | 0.02† |
| Ascending aorta | 36.5±6.3 | 36.8±7.5 | 39.1±6.1 | 35.8±6.5 | 0.005‡ |
| Yearly rate, mm/year | |||||
| Annulus | 0.05±0.3 | 0.02±0.1 | 0.06±0.2 | 0.05±0.1 | 0.49 |
| Valsalva sinuses | 0.24±0.3 | 0.25±0.5 | 0.19±0.3 | 0.20±0.4 | 0.61 |
| Sinotubular junction | 0.24±0.6 | 0.12±0.4 | 0.21±0.5 | 0.05±0.3 | 0.29 |
| Ascending aorta | 0.39±0.5 | 0.51±0.8 | 0.40±0.5 | 0.33±0.6 | 0.54 |
*Significant difference between typical and atypical, regardless of raphe.
†Significant difference between typical and atypical with raphe.
‡Significant difference between typical with raphe and other subgroups.
AR, aortic regurgitation; AS, aortic stenosis; BAV, bicuspid aortic valve.