Table 3

Risk factors associated with increased likelihood of higher conduit regurgitation grade and increased mean/peak conduit gradient

FactorEstimate±SEp ValueReliability
Pulmonary conduit regurgitation grade
Overall phase
Risk factors related to all conduits
 Use of allograft (as compared to bioprosthesis)1.35±0.34<0.00150.8
 Female patient gender0.90±0.16<0.00189.3
Risk factors related to allografts only
 Surgical adjustment of allograft0.64±0.200.001100
 Antibiotic treatment of allograft1.01±0.23<0.00183.3
 Male gender of donor allograft0.33±0.150.03299.4
Early phase
 Absence of allograft sclerosis or fibrosis−2.30±0.39<0.00169.9
Late phase
 Absence of allograft fenestrations−0.57±0.230.01292.3
Mean conduit gradient
Risk factors related to all conduits
 Male patient gender0.07±0.01<0.00195
 Younger patient age*−0.16±0.02<0.001100
 Use of bioprosthesis (as compared to allograft)0.21±0.04<0.00196
 Smaller conduit diameter†−0.27±0.06<0.00196
Risk factors related to allografts only
 Younger age of allograft donor‡−0.07±0.020.012100
Peak conduit gradient
Risk factors related to all conduits
 Smaller conduit diameter†−1.42±0.27<0.00198
 Use of bioprosthesis (as compared to allograft)0.81±0.170.00276
 Younger patient age*−0.75±0.08<0.001100
 Male patient gender0.41±0.05<0.00159
 Recent date of surgery§0.16±0.080.03973
 Interrupted proximal suture line0.42±0.180.017100
Risk factors related to allografts only
 Non-heart beating donor of allograft0.14±0.070.02496
 Younger age of allograft donor‡−0.35±0.10<0.001100
  • *Patient age/40.

  • †Conduit diameter/25.

  • ‡Donor age/47.

  • §Interval first–last surgery in database/15.