Demographics and rates of heart failure in previous large studies of women with structural heart disease
| First author | Year | N | Percentage of patients with congenital heart disease (CHD) | Baseline NYHA Class | History of heart failure prior to pregnancy | Heart failure episode during pregnancy | Maternal death | Diuretic use prior to pregnancy |
|---|---|---|---|---|---|---|---|---|
| Siu3 CARPREG | 2001 | 599 | 74 | I–II: 96% III: 4% | 2.6% | 7% | 0.5% | 1% |
| Khairy2 Pregnancy outcomes in women with CHD | 2006 | 53 | 100 | I—87.8% II—12.2% | 7.8% | 16.7% | 0 | 7.8% |
| Drenthen1 ZAHARA | 2010 | 1302 | 100 | NR | NR | 1.6% | NR* | NR |
| Roos-Hesselink5 ROPAC | 2012 | 1321 | 66 | I—70% IV—0.3% | 11% | 13.1% | 1% | NR |
*Not reported as the data were derived only from a survivor cohort.
CARPREG, cardiac disease in pregnancy; NR, not reported; ROPAC, registry on pregnancy and cardiac disease.