Arrhythmia, exercise, and CMR data
| Arrhythmia data | All patients (N=873) | Outcome (death/VT) (N=32) | No outcome (N=841) | p Value |
|---|---|---|---|---|
| QRS duration (ms) | 146±28 (72–226) | 154±32 (86–208) | 145±28 (72–226) | 0.08 |
| Atrial flutter | 60 (7%) | 5 (16%) | 55 (7%) | 0.06 |
| Atrial fibrillation | 37 (4%) | 10 (31%) | 27 (3%) | <0.001 |
| Non-sustained ventricular tachycardia | 81 (9%) | 10 (31%) | 71 (8%) | <0.001 |
| Prior ablation | 48 (5%) | 4 (13%) | 44 (5%) | 0.09 |
| Permanent pacemaker | 13 (1%) | 0 (0%) | 13 (2%) | 1.00 |
| Implantable defibrillator | 45 (5%) | 7 (22%) | 38 (5%) | <0.001 |
| Exercise data | All patients (N=551) | Outcome (death/VT) (N=11) | No outcome (N=540) | p Value |
| Peak oxygen consumption (mL/kg/min) | 25 (2–53) | 14 (8–27) | 25 (2–53) | 0.001 |
| Percent predicted peak oxygen consumption | 64 (18–160) | 46 (21–77) | 64 (18–160) | 0.003 |
| Ventilatory anaerobic threshold (mL/kg/min) | 15 (6–44) | 11 (7–15) | 15 (6–44) | 0.004 |
| Percent predicted ventilatory anaerobic threshold | 41 (22–79) | 36 (29–49) | 41 (22–79) | 0.12 |
| CMR data | All patients (N=873) | Outcome (death/VT) (N=32) | No outcome (N=841) | p Value |
| RV end-diastolic volume index (mL/m2) | 152±49 | 145±42 | 153±50 | 0.34 |
| RV end-systolic volume index (mL/m2) | 79±35 | 87±37 | 79±35 | 0.25 |
| RV EF (%) | 49±9 | 43±11 | 49±9 | 0.004 |
| RV EF z score | −1.9±2.0 | −3.2±2.4 | −1.9±2.0 | 0.005 |
| RV mass index (g/m2) | 36±16 | 58±32 | 35±14 | 0.001 |
| RV mass z score | 3.6±3.0 | 7.6±5.8 | 3.4±2.7 | <0.001 |
| RV mass/volume (g/mL) | 0.24±0.1 | 0.42±0.2 | 0.24±0.1 | <0.001 |
| Pulmonary regurgitation (%) | 35±17 | 32±16 | 35±17 | 0.34 |
| LV end-diastolic volume index (mL/m2) | 86±22 | 89±38 | 86±21 | 0.64 |
| LV end-systolic volume index (mL/m2) | 37±15 | 44±26 | 36±14 | 0.12 |
| LV EF (%) | 58±8 | 53±10 | 58±8 | 0.01 |
| LV EF z score | −1.34±1.6 | −2.57±2.2 | −1.29±1.6 | 0.004 |
| LV mass index (g/m2) | 53±19 | 81±53 | 52±16 | 0.008 |
| LV mass/volume (g/mL) | 0.63±0.2 | 0.90±0.4 | 0.62±0.2 | 0.002 |
| RV/LV end-diastolic volume ratio | 1.84±0.61 | 1.75±0.61 | 1.84±0.61 | 0.41 |
QRS duration and CMR data are presented as mean±SD (range). Exercise data are presented as median (range).
CMR, cardiac MR; VT, ventricular tachycardia.