Baseline characteristics of included cohort studies
| Study | Location | Design | Population | Total | Mean age (years) | Male (%) | BMI (kg/m2) | HTN (%) | DM (%) | CAD (%) | Stroke (%) | OH definition | OH prevalence (%) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Masaki et al16 | USA | Prospective cohort | Older Japanese American men living in Hawaii | 3522 | 82.0 | 100.0 | 23.5 | 54.1 | 11.8 | 16.6 | 3.1 | SBP decline ≥20 mm Hg or DBP decline ≥10 mm Hg at 3 min from supine to standing | 6.9 |
| Fisher et al 20 | Australia | Prospective cohort | Older residents of long-term healthcare facilities | 179 | 83.2 | 19.6 | NR | 46.9 | 6.7 | 36.9 | 22.3 | SBP decline ≥20 mm Hg or DBP decline ≥10 mm Hg within 3 min from supine to standing | 22.9 |
| Sasaki et al 17 | Japan | Prospective cohort | CRF patients | 304 | 63.0 | 74.3 | 20.2 | 23.1 | 42.4 | 35.2 | 32.2 | SBP decline ≥20 mm Hg or DBP decline ≥10 mm Hg at 3 min from supine to standing for more than three of the five measurements | 42.1 |
| Rose et al 3 | USA | Prospective cohort | Community-living middle-aged individuals | 13 152 | 54.2 | 45.0 | 27.7 | 34.0 | 12.4 | 7.3 | 5.5 | SBP decline ≥20 mm Hg or DBP decline ≥10 mm Hg within 3 min from supine to standing | 5.1 |
| Weiss et al 21 | Israel | Prospective cohort | Older patients discharged from geriatric wards | 471 | 81.5 | 48.2 | 25.1 | 62.6 | 29.3 | 56.7 | 31.8 | SBP decline ≥20 mm Hg or DBP decline ≥10 mm Hg after 2 min from supine to standing for more than two of the three measurements | 34.2 |
| Vewoert 2008 | The Netherlands | Prospective cohort | Community-living individuals | 5064 | 68.1 | 38.4 | 26.2 | 26.9 | 8.9 | 0 | 0 | SBP decline ≥20 mm Hg or DBP decline ≥10 mm Hg at 1, 2 or 3 min from supine to standing | 17.8 |
| Fedorowski et al 11 | Sweden | Prospective cohort | Population-based middle-aged individuals | 32 797 | 45.6 | 68.2 | 24.6 | 40.3 | 4.8 | 0 | 0 | SBP decline ≥ 20 mm Hg or DBP decline ≥10 mm Hg within 3 min from supine to standing | 6.6 |
| Badia et al 19 | Spain | Prospective cohort | Community-living older individuals | 323 | 85.5 | 37.5 | NR | 75.5 | 17.4 | 13.9 | 18.9 | SBP decline ≥ 20 mm Hg or DBP decline ≥10 mm Hg within 3 min from supine to standing | 9.6 |
| Lagro (2012) | The Netherlands | Retrospective cohort | Older patients in fall clinics | 313 | 78.7 | 36.6 | 26.4 | 46.9 | 18.8 | NR | NR | SBP decline ≥20 mm Hg or DBP decline ≥10 mm Hg within 3 min from supine to standing | 53.7 |
BMI, body mass index; CAD, coronary artery disease; CRF, chronic renal failure; DBP, diastolic blood pressure; DM, diabetes mellitus; HTN, hypertension; NR, not reported; OH, orthostatic hypotension; SBP, systolic blood pressure.