Spearman partial correlation coefficient (p value) | |||
---|---|---|---|
Parameter and model | IL-6 | CRP | TNF-α R1 |
Flow-mediated dilation % | |||
Univariate | −0.115 (<0.001) | −0.010 (0.58) | −0.096 (<0.001) |
Multivariate* | −0.070 (<0.001) | −0.029 (0.09) | 0.020 (0.40) |
Multivariate† | −0.042 (0.02) | 0.008 (0.64) | 0.014 (0.570) |
*Multivariate analysis adjusted for age and gender.
†Multivariate analysis adjusted for age, gender, race/ethnicity, education, income, low-density lipoprotein, glucose, diabetes, hypertension status and treatment, waist circumference, triglycerides, baseline brachial diameter and use of medications that may alter inflammation.
CRP, C reactive protein; IL-6, interleukin-6; TNF-α R1, tumour necrosis factor-α receptor 1.