Baseline demographics of the patients with and without severely calcified lesions
| All studied patients (n=6296) | Patients with severely calcified lesions (n=1291) | Patients without severe calcifications (n=5005) | p Value | |
|---|---|---|---|---|
| Age (years) | 64 (56–72) | 69 (62–75) | 63 (55–71) | <0.001 |
| Male (%) | 4740 (75.3) | 957 (74.1) | 3783 (75.6) | 0.280 |
| BMI | 27.1 (24.7–30.0) | 27.0 (24.2–30.0) | 27.2 (24.8–30.1) | 0.001 |
| Hypertension | 4328 (69.4) | 969 (75.5) | 3359 (67.7) | <0.001 |
| Hypercholesterolaemia (%) | 4056 (65.2) | 899 (70.2) | 3157 (63.9) | <0.001 |
| Diabetes mellitus (%) | 1453 (23.2) | 1079 (21.7) | 374 (29.0) | <0.001 |
| Peripheral vascular disease (%) | 1745 (30.7) | 397 (32.1) | 1348 (30.3) | 0.214 |
| Cerebrovascular disease (%) | 182 (4.9) | 73 (7.2) | 109 (4.0) | <0.001 |
| Creatinine > 200 mol/L | 61 (1.1) | 20 (1.6) | 41 (0.9) | 0.025 |
| Positive smoking history (%) | 3257 (52.1) | 648 (50.4) | 2609 (52.6) | 0.161 |
| LV systolic function | 0.712 | |||
| Normal LV function (%) | 3838 (78.4) | 833 (77.6) | 3005 (78.7) | |
| Moderate LV dysfunction (%) | 865 (17.7) | 196 (18.2) | 669 (17.5) | |
| Severe LV dysfunction (%) | 191 (3.9) | 45 (4.2) | 146 (3.8%) | |
| Unstable presentation (%) | 3349 (53.2) | 672 (52.1) | 2677 (53.5) | 0.357 |
| History of previous MI (%) | 1745 (30.7) | 397 (32.1) | 1348 (30.3) | 0.214 |
| Syntax score | 15 (9–23) | 25 (18–34) | 13 (7–20) | <0.001 |
| Complete revascularisation (%) | 1086 (53) | 339 (48) | 550 (55.6) | 0.001 |
| Treatment with 2nd generation DES (%) | 2709 (43.0) | 375 (29.0) | 2334 (46.5) | <0.001 |
BMI, Body Mass Index; MI, myocardial infarction; DES, drug-eluting stent.