Table 2

Variables associated with EVS: bivariate and multivariate propensity logistic regression analyses

Bivariate regressionMultivariate regression
OR95% CIp ValueOR95% CIp Value
Female sex0.530.37 to 0.780.00090.760.49 to 1.160.20
Age <65 years2.792.01 to 3.87<0.00012.401.66 to 3.48<0.0001
Number of comorbidities*0.790.68 to 0.920.002
Hypertension0.660.48 to 0.920.013
Diabetes mellitus0.610.41 to 0.920.027
Current smoker2.001.36 to 2.950.0007
Intravenous drug users3.841.25 to 11.800.009
Previous IE1.510.84 to 2.720.16
Fever0.750.45 to 1.240.26
Streptococcal IE1.230.89 to 1.690.20
Staphylococcal IE0.750.53 to 1.080.12
Location of IE (vs mitral)<0.00010.0005
 Aortic1.921.34 to 2.751.911.25 to 2.91
 Aortic+mitral3.772.30 to 6.182.891.65 to 5.06
Valve perforation3.792.32 to 6.22<0.00013.041.78 to 5.430.0002
Intracardiac abscess3.202.11 to 4.87<0.00012.521.57 to 4.060.0001
Dehiscence2.291.02 to 5.130.040
Severe regurgitation3.872.75 to 5.44<0.00013.042.07 to 4.48<0.0001
Cardiac failure2.121.49 to 3.020.00011.881.24 to 2.860.01
Septic shock1.961.06 to 3.640.091
Vascular event1.320.96 to 1.810.086
Creatinine >180 µmol/L1.000.70 to 1.410.48
CRP >120 mg/L0.700.50 to 0.970.085
Survey 1999/20081.110.81 to 1.520.52
  • *Per 1 unit increment.

  • CRP, C reactive protein; EVS, early valve surgery; IE, infective endocarditis.