Univariate predictors of appropriate ICD therapy after generator replacement
| Variable | Rate of events, n/N (%) | HR (95% CI) | p Value | |
|---|---|---|---|---|
| Present | Absent | |||
| Ischaemic cardiomyopathy | 21/157 (13) | 8/109 (7) | 2.02 (0.90 to 4.57) | 0.09 |
| LVEF <25%* | 10/82 (12) | 12/143 (8) | 1.48 (0.64 to 3.42) | 0.36 |
| Renal insufficiency | 7/59 (12) | 22/207 (11) | 1.02 (0.43 to 2.40) | 0.96 |
| Diabetes mellitus | 5/55 (9) | 24/211 (11) | 0.82 (0.31 to 2.15) | 0.69 |
| CRT-ICD | 11/116 (9) | 18/150 (12) | 0.77 (0.36 to 1.62) | 0.49 |
| NYHA ≥III | 9/106 (8) | 20/160 (12.5) | 0.66 (0.30 to 1.44) | 0.29 |
| Advanced age (age >70 years at replacement) | 4/68 (6) | 25/198 (13) | 0.49 (0.17 to 1.41) | 0.19 |
CRT, cardiac resynchronisation therapy; ICD, implantable cardioverter-defibrillator; NYHA, New York Heart Association.
*LVEF data were available for 225 patients.