Cecchin et al25 | Dubin et al24 | Janousek et al23 | |
---|---|---|---|
Number of patients | 60 | 103 | 109 |
Median age (year) | 15 | 13 | 17 |
Baseline data | |||
NHYA class | |||
NYHA I (%) | 27 | 14 | Median NYHA Class 2.5 |
NYHA II (%) | 42 | 48 | |
NYHA III-IV (%) | 32 | 38 | |
Systemic ventricular EF | 36 | 26 | 27 |
% CHD | 77 | 71 | 80 |
% single ventricle | 22 | 7 | 4 |
% systemic RV | 12 | 17 | 33 |
QRS (ms) | 149 | 166 | 160 |
Post-CRT data | |||
Change NYHA class | NR | NR | Decreased 1.5 grades |
Systemic ventricular EF (%) | 43 | 40 | Median change +12 |
QRS (ms) | 120 | 126 | 130 |
% with improvement in EF or NYHA class | 87 | 76 | 72 |
Predictors of poor CRT response | Systemic RV | Higher baseline EF | Dilated cardiomyopathy, high baseline NYHA Class |
Modified with permission from van der Hulst et al.27
CHD, congenital heart disease; CRT, cardiac resynchronisation therapy; NYHA, New York Heart Association.