Table 1

Baseline characteristics by neo-aortic dilation

AllStableDilating
β<0.34β>0.34
N=77N=32N=33p Value
Age (years)23±526±623±30.035
Neo-aortic diameter (cm)3.6±0.53.8±0.63.5±0.50.018
Male49 (64%)21 (66%)25 (76%)0.369
Systolic blood pressure122±15120±16125±140.258
Diastolic blood pressure70±1070±1070±110.815
Era0.708
 Before 198734 (44%)17 (53%)16 (49%)
 After 198745 (58%)15 (47%)17 (52%)
Surgical variables
 Age at operation (days)7 (3–50)6 (2–85)9 (4–58)0.450
 Weight at operation (kg)3.5 (3.1–4.0)3.5 (3.1–4.8)3.5 (3.1–4.1)0.853
 Time on bypass (min)223±53209±42223±530.268
 Clamp time (min)116±34109±30119±380.279
Childhood events
 Neo-pulmonary stenosis16 (20%)5 (16%)7 (21%)0.562
 Neo-aortic operation*6 (8%)2 (6%)4 (12%)0.672
 Supraventricular arrhythmia4 (5%)2 (6%)1 (3%)0.613
 Heart failure1 (1%)0 (0%)1 (3%)1.000
Anatomy
 TGA-IVS50 (65%)20 (63%)22 (67%)0.725
 TGA-VSD17 (22%)9 (28%)7 (21%)0.518
 Taussig–Bing9 (12%)2 (6%)4 (12%)0.672
 TGA-VSD-PS1 (1%)1 (3%)0 (0%)0.492
Coexisting anomalies
 Abnormal coronary pattern15 (20%)4 (13%)7 (21%)0.488
 Aortic coarctation7 (9%)4 (13%)2 (6%)0.370
 Bicuspid neo-AV3 (5%)3 (9%)0 (0%)0.114
 PDA57 (75%)20 (67%)23 (72%)0.657
 ASD34 (47%)12 (43%)13 (41%)0.861
Neo-aortic regurgitation
 None37 (48%)14 (44%)16 (49%)0.616
 Mild28 (36%)13 (41%)11 (33%)0.606
 Moderate8 (10%)4 (13%)4 (12%)1.000
 Severe0 (0%)0 (%)0 (0%)
 Valve prosthesis3 (4%)1 (3%)2 (6%)0.573
N exams3.7±2.14.4±2.34.0±1.50.517
Time-span analysed4.2±3.05.4±2.64.6±2.40.188
Serial examinations65 (82%)
  • Bold p-value <0.05.

  • *Includes neo-aortic valve replacement (n=3), root replacement (n=0) and coarctation repair (n=3); data are mean±SD, number of patients (percentage) or median (IQR).

  • ASD, atrial septal defect; AV, aortic valve; IVS, intact ventricular septum; PDA, patent ductus arteriosus; PS, pulmonary stenosis; TGA, transposition of the great arteries; VSD, ventricular septal defect.