Baseline characteristics by neo-aortic dilation
| All | Stable | Dilating | ||
|---|---|---|---|---|
| β<0.34 | β>0.34 | |||
| N=77 | N=32 | N=33 | p Value | |
| Age (years) | 23±5 | 26±6 | 23±3 | 0.035 |
| Neo-aortic diameter (cm) | 3.6±0.5 | 3.8±0.6 | 3.5±0.5 | 0.018 |
| Male | 49 (64%) | 21 (66%) | 25 (76%) | 0.369 |
| Systolic blood pressure | 122±15 | 120±16 | 125±14 | 0.258 |
| Diastolic blood pressure | 70±10 | 70±10 | 70±11 | 0.815 |
| Era | 0.708 | |||
| Before 1987 | 34 (44%) | 17 (53%) | 16 (49%) | |
| After 1987 | 45 (58%) | 15 (47%) | 17 (52%) | |
| Surgical variables | ||||
| Age at operation (days) | 7 (3–50) | 6 (2–85) | 9 (4–58) | 0.450 |
| Weight at operation (kg) | 3.5 (3.1–4.0) | 3.5 (3.1–4.8) | 3.5 (3.1–4.1) | 0.853 |
| Time on bypass (min) | 223±53 | 209±42 | 223±53 | 0.268 |
| Clamp time (min) | 116±34 | 109±30 | 119±38 | 0.279 |
| Childhood events | ||||
| Neo-pulmonary stenosis | 16 (20%) | 5 (16%) | 7 (21%) | 0.562 |
| Neo-aortic operation* | 6 (8%) | 2 (6%) | 4 (12%) | 0.672 |
| Supraventricular arrhythmia | 4 (5%) | 2 (6%) | 1 (3%) | 0.613 |
| Heart failure | 1 (1%) | 0 (0%) | 1 (3%) | 1.000 |
| Anatomy | ||||
| TGA-IVS | 50 (65%) | 20 (63%) | 22 (67%) | 0.725 |
| TGA-VSD | 17 (22%) | 9 (28%) | 7 (21%) | 0.518 |
| Taussig–Bing | 9 (12%) | 2 (6%) | 4 (12%) | 0.672 |
| TGA-VSD-PS | 1 (1%) | 1 (3%) | 0 (0%) | 0.492 |
| Coexisting anomalies | ||||
| Abnormal coronary pattern | 15 (20%) | 4 (13%) | 7 (21%) | 0.488 |
| Aortic coarctation | 7 (9%) | 4 (13%) | 2 (6%) | 0.370 |
| Bicuspid neo-AV | 3 (5%) | 3 (9%) | 0 (0%) | 0.114 |
| PDA | 57 (75%) | 20 (67%) | 23 (72%) | 0.657 |
| ASD | 34 (47%) | 12 (43%) | 13 (41%) | 0.861 |
| Neo-aortic regurgitation | ||||
| None | 37 (48%) | 14 (44%) | 16 (49%) | 0.616 |
| Mild | 28 (36%) | 13 (41%) | 11 (33%) | 0.606 |
| Moderate | 8 (10%) | 4 (13%) | 4 (12%) | 1.000 |
| Severe | 0 (0%) | 0 (%) | 0 (0%) | – |
| Valve prosthesis | 3 (4%) | 1 (3%) | 2 (6%) | 0.573 |
| N exams | 3.7±2.1 | 4.4±2.3 | 4.0±1.5 | 0.517 |
| Time-span analysed | 4.2±3.0 | 5.4±2.6 | 4.6±2.4 | 0.188 |
| Serial examinations | 65 (82%) | – | – | – |
Bold p-value <0.05.
*Includes neo-aortic valve replacement (n=3), root replacement (n=0) and coarctation repair (n=3); data are mean±SD, number of patients (percentage) or median (IQR).
ASD, atrial septal defect; AV, aortic valve; IVS, intact ventricular septum; PDA, patent ductus arteriosus; PS, pulmonary stenosis; TGA, transposition of the great arteries; VSD, ventricular septal defect.