Table 1

Clinical characteristics and exercise capacity data according to tertiles of peak-ex BNP level

Whole Cohort n=211Tertile 1 (6–42 pg/mL) n=71Tertile 2 (43–91 pg/mL) n=70Tertile 3 (92–956 pg/mL) n=70p Value†
Clinical data
 Age, years68±1165±1269±10*69±10*0.03
 Male gender, %64%63%66%63%0.91
 Height, cm167±8167±7168±10166±80.50
 Weight, kg74±1376±1276±1272±130.21
 Body surface area, m21.82±0.181.82±0.181.83±0.181.81±0.190.71
 Body mass index, kg/m226.6±3.727.1±3.926.8±3.526.0±3.60.27
 Heart rate, beats/min70±1271±1270±1070±130.99
 History of hypertension, %53%57%49%53%0.65
 Systolic blood pressure, mm Hg141±21142±24139±17142±210.71
 Diastolic blood pressure, mm Hg77±1179±1174±10*77±110.04
 Hypercholesterolaemia, %46%48%43%47%0.83
 Diabetes, %14%13%12%17%0.44
 History of smoking, %27%24%31%28%0.65
 Resting BNP level, pg/mL43 (24–81)16 (9–26)45 (39–60)101 (76–133)By design
Exercise testing data
 Duration, min9.1±3.19.0±2.68.9±2.99.4±3.60.69
 Peak-ex workload, watts99±35102±38101±3594±330.35
 Peak-ex heart rate, beats/min120±19124±20119±16118±190.13
 Percent of predicted maximal heart rate, %91±1292±1291±1190±140.83
 Peak-ex systolic blood pressure, mm Hg179±23184±23177±24177±220.17
 Peak-ex diastolic blood pressure, mm Hg87±1490±1485±1486±130.09
 Peak-ex BNP level, pg/mL58 (29–115)20 (13–30)59 (53–74)146 (115–201)By design
  • Values are mean±SD except for BNP data which are median (IQR).

  • †p Value of the one-way ANOVA. The following symbols indicate the significance of the Tukey's post hoc test: *p<0.05 from ‘Tertile 1’.

  • BNP, B-type natriuretic peptide; Peak-ex, peak-exercise.