Table 2

Resting and peak-exercise echocardiographic data according to tertiles of peak-exercise BNP level

	Whole cohort n=211	Tertile 1 (6–42 pg/mL) n=71	Tertile 2 (43–91 pg/mL) n=70	Tertile 3 (92–956 pg/mL) n=70	p Value†
Resting echocardiographic data
Stroke volume, mL	84±19	86±20	86±19	79±19	0.05
Stroke volume index, mL/m²	46±11	48±11	47±11	44±11	0.13
Peak aortic jet velocity, m/s	4.0±0.7	3.7±0.7	4.1±0.7*	4.1±0.8*	0.001
Peak transvalvular gradient, mm Hg	66±24	59±21	69±23*	71±25*	0.006
Mean transvalvular gradient, mm Hg	41±15	37±13	43±15*	43±16*	0.02
Aortic valve area, cm²	0.93±0.21	0.98±0.19	0.90±0.20*	0.90±0.24*	0.03
Indexed aortic valve area, cm²/m²	0.51±0.12	0.54±0.11	0.49±0.10*	0.50±0.13*	0.03
Indexed left atrial area, cm²/m²	11.6±3.3	11.0±3.0	10.9±3.1	12.8±3.4*‡	0.0007
E to e′	10.8±4.2	9.9±3.9	11.2±3.8	11.4±4.8	0.15
Pulmonary hypertension, %	3%	1%	1%	7%	0.09
Relative wall thickness	0.51±0.12	0.48±011	0.51±0.09	0.54±0.15*	0.04
LV mass index, g/m²	124±45	123±47	126±47	123±41	0.88
LVEF, %	66±7	67±8	66±6	66±8	0.66
Valvulo-arterial imp., mm Hg/mL m²	4.1±1.1	3.9±0.8	4.0±1.0	4.5±1.3*‡	0.003
Peak-exercise-stress echocardiographic data
Stroke volume, mL	94±29	91±27	94±32	97±30	0.49
Stroke volume index, mL/m²	49±16	47±15	49±17	50±16	0.49
Peak aortic jet velocity, m/s	4.6±0.8	4.3±0.7	4.7±0.7*	4.7±0.8*	0.01
Peak transvalvular gradient, mm Hg	86±28	78±27	89±26*	90±30*	0.02
Mean transvalvular gradient, mm Hg	53±19	48±16	56±18*	56±21*	0.01
Aortic valve area, cm²	1.01±0.29	1.09±0.26	0.97±0.29*	0.98±0.30	0.03
Indexed aortic valve area, cm²/m²	0.56±0.16	0.60±0.15	0.53±0.16*	0.55±0.17	0.03
Pulmonary hypertension, %	32%	23%	34%	39%	0.10
LVEF, %	68±9	68±10	69±8	67±9	0.42
Valvulo-arterial imp., mm Hg/mL m²	5.1±1.9	5.2±1.8	5.2±1.9	5.0±1.9	0.82

Values are mean±SD.
†p Value of the one-way ANOVA. The following symbols indicate the significance of the Tukey's post hoc test: *p<0.05 from ‘Tertile 1’; ‡p<0.05 from ‘Tertile 2’.
BNP, B-type natriuretic peptide.