Table 2

Effects of several drugs on non-consecutive QTn variability

DrugEffectDrugEffect
β-BlockerAntidepressants
 CarvedilolW36 ClonidineW131
 MetoprololW36 PemolineW130
 SotalolW26 W50 W83 W124↑/= VenlafaxineW108
Antiarrhythmics DuloxetineW108
 DigoxinW124 NortriptylineW101
 AmiodaroneW83= YohimbineW131
 IbutilideW125 FluoxetineW130=
AtorvastatinW127= FluvoxamineW89=
β-Sympaticomimetics SertralineW89=
 DobutamineW62 CitalopramW89 W108↑/=
 EpinephrineW126 ParoxetineW101 W108↑/=
 IsoproterenolW100Magnesium sulfateW124
SevofluraneW128SildenafilW129
  • QTn, QT variability normalised. ↑ indicates an increase in QT variability, ↓ indicates a decrease in QT variability, = indicates no effect on QT variability.