Table 2

Comparison of incidence and HR of ACS stratified by sex and age between patients with and without scrub typhus

Scrub typhus
NoYes
VariablesEventPYRate†EventPYRate†IRR(95% CI)Adjusted HR‡ (95% CI)
All209108 6611.928326 7413.101.61 (1.48 to 1.76)***1.37 (1.05 to 1.77)*
Sex 
 Female5537 9641.452992053.152.17 (1.90 to 2.50)***1 (Reference)
 Male15470 6972.185417 3363.081.41 (1.27 to 1.58)***2.03 (1.57 to 2.62)***
Stratify age 
 ≤341444 6700.31511 2680.441.42 (1.20 to 1.67)***1 (Reference)
 35–493832 8141.162379352.902.50 (2.15 to 2.91)***4.49 (2.68 to 7.53)***
 50–649023 0333.913756286.571.68 (1.43 to 1.99)***11.2 (6.82 to 18.3)***
 ≥656781438.231819109.421.15 (0.87 to 1.51)17.7 (10.5 to 29.8)***
  • *p<0.05, ***p<0.001.

  • †Rate, incidence rate, per 1000 person-years.

  • ‡Adjusted HR: multivariable analysis including age, sex, and comorbidities of hypertension, diabetes, hyperlipidaemia, CVA, COPD, CHF, asthma and CAD.

  • ACS, acute coronary syndrome; CAD, coronary artery disease; CHF, congestive heart failure; COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular accident; IRR, incidence rate ratio; PY, person-years.