Predictive accuracy of echocardiographic parameters of stenosis severity for aortic valve events
| c-statistics | |||||
|---|---|---|---|---|---|
| AUC | 95% CI | p Value* | Sensitivity | Specificity | |
| MPG | 0.68 | 0.63 to 0.73 | <0.001 | 62.6 | 66.5 |
| Jet velocity | 0.67 | 0.62 to 0.72 | <0.001 | 58.8 | 68.3 |
| AVA | 0.56 | 0.51 to 0.62 | 46.0 | 70.5 | |
| AVAindex | 0.59 | 0.53 to 0.64 | 0.15 | 51.2 | 67.9 |
| VR | 0.62 | 0.57 to 0.67 | 0.06 | 84.4 | 37.9 |
| VR-adjusted AVA | 0.62 | 0.57 to 0.67 | 0.02 | 77.3 | 45.1 |
| VR-adjusted MPG | 0.69 | 0.64 to 0.74 | <0.001 | 64.0 | 68.3 |
| SVI (VTI)† | 0.48 | 0.42 to 0.53 | <0.001 | ||
| SVI (Teichholz)† | 0.49 | 0.43 to 0.54 | <0.001 | ||
Predictive accuracy of echocardiographic parameters of stenosis severity for aortic valve events in 435 patients with low gradient severe aortic stenosis. The area under the receiver operating characteristic curve (AUC) and the 95% CIs are shown for the unadjusted echocardiographic parameters, for VR-adjusted MPG and VR-adjusted AVA, and for stroke volume index derived from velocity time integral (VTI) and from the Teichholz formula.
*p Value vs AVA.
†No meaningful values for maximum sensitivity or specificity could be derived for SVI.
AVA, aortic valve area; MPG, mean pressure gradient; VR, velocity ratio.