Table 1

Baseline maternal characteristics of 225 cohorts presenting in modified WHO I–IV

All patients (n=225)WHO I (n=73)WHO II–IV (n=152)p Value
Age at enrolment (years)28.6±6.428.8±7.028.5±6.10.97
Ethnicity, n (%)
 African or black101 (45)23 (32)79 (52)<0.0001
 Mixed72 (32)15 (20)56 (37)
 White34 (15)19 (26)15 (10)
 Other (Arab, Indian, other)18 (8)16 (22)2 (1)
General medical history, n (%)
 Chronic hypertension12 (5)2 (3)10 (7)0.35
 Hypercholesterolaemia3 (1)0 (0)3 (2)0.55
 HIV38 (12)2 (3)36 (24)<0.0001
 Syphilis1 (0.4)0 (0)1 (1)1.00
 Tuberculosis4 (2)0 (0)4 (3)0.31
Clinical history and presentation, n (%)
 Previously known CVD93 (41)40 (55)53 (35)0.006
 Previously operated CVD57 (25)27 (37)30 (20)0.007
 NYHA FC I-II193 (86)73 (100)120 (79)<0.0001
 NYHA FC III-IV32 (14)0 (0)32 (21)
 SBP in mmHg119±15118±13119±160.97
 DBP in mm Hg74±1175±1074±110.53
 Heart rate in bpm86±1878±1290±19<0.0001
 Weight in kg72.1±16.872.5±12.572.1+18.60.30
Obstetric history, n (%)
 Gestational age at presentationn=188n=66n=122
 <12 weeks7 (4)3 (5)4 (3)
 12–24 weeks84 (45)32 (48)52 (43)0.65
 >24 weeks97 (52)31 (47)66 (54)
 Gravida (median, range)2 (1–7)2 (1–6)2 (1–7)0.0002
 Para (median, range)1 (0–5)1 (0–4)1 (0–5)0.003
 Nulliparous, n (%)65 (29)29 (40)36 (24)0.02
 Twin pregnancies3 (1)0 (0)3 (2)0.30
  • A number of women were either not pregnant or presented postpartum. Gestational age at presentation percentages calculated towards 187, 66 and 121, respectively.

  • CVD, cardiovascular disease; DBP, diastolic blood pressure; NYHA FC, New York Heart Association Functional Class; SBP, systolic blood pressure.