Table 4

The association of female sex with rates of major CV events, ischaemic CV events and death in time-varying multivariate Cox analyses adjusting for active study treatment, age and hypertension, as well as time-varying ELI, low EF, low MWS and abnormal LV geometry

HR (95% CI)p Value
Major CV events0.83 (0.69 to 0.99)0.04
Aortic valve events0.85 (0.70 to 1.02)0.08
Ischaemic events0.60 (0.46 to 0.79)<0.001
 stroke0.47 (0.26 to 0.85)0.01
 coronary artery bypass grafting0.49 (0.34 to 0.71)<0.001
 non-fatal myocardial infarction1.15 (0.52 to 2.54)0.724
 hospitalisation for unstable angina0.62 (0.17 to 2.20)0.456
 percutaneous coronary intervention0.62 (0.21 to 1.82)0.386
Death0.69 (0.49 to 0.99)0.04
  • CV, cardiovascular; ELI, energy loss index; MWS, midwall shortening.