The association of female sex with rates of major CV events, ischaemic CV events and death in time-varying multivariate Cox analyses adjusting for active study treatment, age and hypertension, as well as time-varying ELI, low EF, low MWS and abnormal LV geometry
| HR (95% CI) | p Value | |
|---|---|---|
| Major CV events | 0.83 (0.69 to 0.99) | 0.04 |
| Aortic valve events | 0.85 (0.70 to 1.02) | 0.08 |
| Ischaemic events | 0.60 (0.46 to 0.79) | <0.001 |
| stroke | 0.47 (0.26 to 0.85) | 0.01 |
| coronary artery bypass grafting | 0.49 (0.34 to 0.71) | <0.001 |
| non-fatal myocardial infarction | 1.15 (0.52 to 2.54) | 0.724 |
| hospitalisation for unstable angina | 0.62 (0.17 to 2.20) | 0.456 |
| percutaneous coronary intervention | 0.62 (0.21 to 1.82) | 0.386 |
| Death | 0.69 (0.49 to 0.99) | 0.04 |
CV, cardiovascular; ELI, energy loss index; MWS, midwall shortening.