Table 1

Main characteristics of included studies

PCI strategies subgroups, n
Primary author, year publishedPeriodSettingPatients or lesionsFFR thresholdAngiography- guided PCIFFR-guided PCIExclusion criteriaMaximum
Prospective studies
 Frohlich, 20142004.01-2011.07MulticentreAll patients treated by PCIN/A37 0902767STEMI3.3 years
 Koo, 20082004.06-2006.01N/ACoronary bifurcation lesions with jailed side branches after DES implantation at the main branches<0.75110110STEMI, LM, totally occluded lesion9 months
 Pijls, 20102006.01-2007.09MulticentreMVD≤0.80496509LM, previous CABG, cardiogenic shock, extremely tortuous or calcified coronary arteries2 years
 Wongpraparut, 20052000.10-2002.08Single-centreStable angina, MVD<0.758057Previous CABG, totally occluded vessels, recent MI30 months
Retrospective studies
 Di Serafino, 20132000.01-2011.06N/AStable or unstable angina, intermediate stenosis in bypass grafts≤0.8015865STEMI, NSTEMI3.8 years
 Li, 20132002.10-2009.12N/APatients referred for coronary revascularisation<0.7562681090STEMI, cardiogenic shock, referral for CABG50.9 months
 Puymirat, 20122004.01-2008.12Single-centreStable or unstable angina, small vessels<0.80495222Patients treated with PCI and stenting for a concomitant large vessel, bypass graft stenting, STEMI, NSTEMI, PCI performed without stent implantation3.3 years
  • CABG, coronary artery bypass graft surgery; DES, drug eluting stent; FFR, fractional flow reserve; LM, left main stenosis; MI, myocardial infarction; MVD, multivessel disease; N/A, not available; NSTEMI, non-ST-segment elevation myocardial infarction; PCI, percutaneous coronary intervention; STEMI, ST-segment elevation myocardial infarction.