Baseline characteristics
| n (%) | |
|---|---|
| Demographic factors | |
| Women | 43 |
| Pregnancies | 50 |
| Mean age at delivery (years) | 35±5 |
| Age range (years) | 27–47 |
| Multiparous | 37 (74) |
| Cardiac diagnosis | |
| Atherosclerosis | 20 |
| Coronary thrombus or embolism | 18 |
| Coronary spasm | 5 |
| Acute coronary syndrome* | 6 |
| Pre-existing coronary risk factors | |
| ≥1 risk factor | 41 (82) |
| Smoking | 11 (22) |
| Family history | 22 (44) |
| Hypertension | 18 (36) |
| Dyslipidaemia | 10 (20) |
| Obesity | 5 (10) |
| Diabetes | 4 (8) |
| Thrombophilia† | 7 (14) |
| Cardiac medications at first antenatal visit‡ n=44 | |
| Any medication | 47 (94) |
| Aspirin/clopidogrel | 28 |
| β-blocker | 19 |
| Heparin | 8 |
| Warfarin | 6 |
| ACE inhibitor | 8 |
| NYHA functional class at first antenatal visit | |
| I | 42 |
| II–IV | 8 |
| LV systolic function§ n=45 | |
| Normal | 27 (54) |
| Mildly reduced | 13 (26) |
| Moderately reduced | 5 (10) |
Note: Coronary anatomy findings are mutually exclusive.
*Acute coronary syndrome documented but aetiology not specified.
†Thrombophilia (Factor V Leiden (n=3), antiphospholipid syndrome (n=3), protein S deficiency (n=1)) confirmed with genetic/lab testing.
‡Medications not documented in six pregnancies.
§LV function assessed by transthoracic echocardiogram at first antenatal visit.
NYHA, New York Heart Association.