Adjusted HR for AF and stroke in patients with ASD with and without closure and the comparison cohort.
| Adjusted* | Adjusted† | |
|---|---|---|
| AF after closure of ASD‡ | 8.2 (6.6 to 10.2) | |
| AF without closure of ASD | 11.9 (10.1 to 13.9) | |
| Stroke after closure of ASD | 2.0 (1.4 to 2.7) | 1.3 (0.9 to 1.9) |
| Stroke from 5 years after closure of ASD | 1.8 (1.2 to 2.6) | 1.1 (0.7 to 1.7) |
| Stroke with no closure of ASD | 2.6 (1.4 to 3.0) | 2.0 (1.5 to 2.6) |
*Adjusted for hypertension, ischaemic heart disease and gender.
†Adjusted for hypertension, ischaemic heart disease, gender and AF.
‡Patients with no prevalent AF and with no use of anticoagulation treatment before closure.
AF, atrial fibrillation; ASD, atrial septal defect.