Top 7 genes with novel and protein altering variants in DCM compared to controls
| Gene tested | DCM n (%) | HVOL n (%) | P value 1-tailed |
|---|---|---|---|
| TTNtv TTNns | 40 (12.0) 85 (25.6) | 6 (1.9) 82 (25.7) | 1.26 × 10–7*0.55 |
| LMNA | 8 (2.4) | 0 | 0.004 |
| DSP | 12 (3.6) | 4 (1.3) | 0.04 |
| RBM20 | 13 (3.9) | 5 (1.6) | 0.05 |
| PKP2 | 10 (3) | 3 (0.9) | 0.05 |
| MYH7 | 12 (3.6) | 5 (1.6) | 0.08 |
| TNNT2 | 4 (1.2) | 0 | 0.06 |
↵* Significant after multiple testing correction, p < 0.0008