Baseline haemodynamic and echocardiographic characteristics of patients according to treatment strategy
| Watchful observation group (n=186) | Early AVR group (n=98) | p Value | |
|---|---|---|---|
| Systolic blood pressure, mm Hg | 136±19 | 129±19 | 0.001 |
| Diastolic blood pressure, mm Hg | 76±12 | 76±13 | 0.71 |
| End-systolic dimension, mm | 29±5 | 30±5 | 0.65 |
| End-diastolic dimension, mm | 49±5 | 48±5 | 0.13 |
| End-systolic volume, mL | 36±13 | 35±16 | 0.96 |
| End-diastolic volume, mL | 90±24 | 91±31 | 0.78 |
| Interventricular septum thickness, mm | 10.8±1.7 | 11.2±2.2 | 0.23 |
| Posterior wall thickness, mm | 10.6±1.6 | 10.9±1.8 | 0.08 |
| EF | 0.63±0.06 | 0.63±0.07 | 0.71 |
| Stroke volume, mL | 76±10 | 74±11 | 0.13 |
| Stroke volume index, mL/m2 | 46±7 | 45±7 | 0.30 |
| LV mass index, g/m2 | 114±41 | 117±42 | 0.64 |
| Aetiology of aortic stenosis, n (%) | |||
| Degenerative | 133 (72) | 54 (55) | 0.006 |
| Bicuspid | 26 (14) | 16 (16) | 0.60 |
| Rheumatic | 27 (15) | 28 (29) | 0.004 |
| Aortic jet velocity, m/s | 3.77±0.20 | 3.85±0.20 | 0.002 |
| Mean gradient, mm Hg | 33.3±4.0 | 35.2±3.9 | <0.001 |
| Aortic valve area, cm2 | 0.86±0.09 | 0.81±0.11 | 0.001 |
| Indexed aortic valve area, cm2/m2 | 0.52±0.07 | 0.50±0.07 | 0.002 |
| Energy loss index, cm2/m2 | 0.53±0.17 | 0.52±0.11 | 0.75 |
| SAC, mL/m2/mm Hg | 0.72±0.21 | 0.79±0.28 | 0.014 |
| Zva, mm Hg/mL/m2 | 3.86±0.93 | 3.88±0.83 | 0.89 |
| RV systolic pressure, mm Hg | 32±9 | 32±9 | 0.71 |
AVR, aortic valve replacement; SAC, systemic arterial compliance; Zva, valvuloarterial impedance.