Table 3

LV assist devices: mechanisms of action and benefits

Haemodynamic support (L/min)AfterloadLV stroke volumeCoronary perfusionLV preloadPCW pressurePT perfusionActive cooling
IABP0.5–1.0 No
Impella2.5–5.0 ↑?↓↓↓↓No
TandemHeart4.0 Unknown↓↓↓↓↓↓Yes
ECMO>4.5 Unknown↓↓↓↓↓↓Yes
  • ECMO, extracorporeal membrane oxygenation; IABP, intra-aortic balloon pump; PCW, pulmonary capillary wedge; PT, peripheral tissues.