Demographic, anatomical and surgical characteristics
| Variable | All patients (N=155) | DSS reoperation (N=32) | No DSS reoperation (N=123) | p Value |
|---|---|---|---|---|
| Male | 94 (60.6%) | 17 (53.1%) | 77 (62.6%) | 0.69 |
| Age at DSS diagnosis, years | 2.5 (0–34.8) | 1.4 (0.0–9.3) | 3.1 (0.0–34.8) | 0.02 |
| Age at DSS resection, years | 5.2 (0.1–35.0) | 3.3 (0.5–8.8) | 5.5 (0.1–34.9) | <0.001 |
| Form of DSS | 0.15 | |||
| Membrane | 109 (70.3%) | 19 (59.4%) | 90 (73.2%) | |
| FMR | 29 (18.7%) | 7 (21.9%) | 22 (17.9%) | |
| Membrane and FMR | 17 (11.0%) | 6 (18.8%) | 11 (8.9%) | |
| Preoperative Doppler gradient, mm Hg | 55 (15–150) | 66 (15–110) | 50 (15–150) | 0.002 |
| Postoperative Doppler gradient, mm Hg | 15 (5–40) | 20 (10–40) | 15 (5–35) | <0.001 |
| Surgical Interventions | ||||
| DSS resection | 155 (100%) | 32 (100%) | 123 (100%) | – |
| Myomectomy | 78 (50.3%) | 18 (56.3%) | 60 (48.8%) | 0.50 |
| Peeling | 0.16 | |||
| No peeling | 91 (58.7%) | 14 (43.8%) | 77 (62.6%) | |
| AoV peeling | 23 (14.8%) | 8 (25.0%) | 15 (12.2%) | |
| MV peeling | 36 (23.2%) | 9 (28.1%) | 27 (22.0%) | |
| AoV and MV peeling | 5 (3.2%) | 1 (3.1%) | 4 (3.3%) | |
| Distance of DSS to AoV (systole) | 0.002 | |||
| ≥7.0 mm | 48 (31.0%) | 3 (9.4%) | 45 (36.6%) | |
| <7.0 mm | 81 (52.3%) | 24 (75.0%) | 57 (46.3%) | |
| Not recorded | 26 (16.8%) | 5 (15.6%) | 21 (17.1%) | |
| AoV morphology | 0.35 | |||
| Triscuspid | 112 (72.3%) | 22 (68.8%) | 90 (73.2%) | |
| Bicuspid/unicuspid | 43 (27.7%) | 10 (31.3%) | 33 (26.8%) | |
| Associated lesions | ||||
| Aortic stenosis | 51 (32.9%) | 17 (53.1%) | 34 (27.6%) | 0.003 |
| VSD | 49 (31.6%) | 9 (28.1%) | 40 (32.5%) | 0.48 |
| Coarctation of aorta | 31 (20.0%) | 9 (28.1%) | 22 (17.9%) | 0.19 |
| Shone syndrome | 22 (14.2%) | 9 (28.1%) | 13 (10.6%) | 0.004 |
| Mitral stenosis | 23 (14.8%) | 10 (31.3%) | 13 (10.6%) | <0.001 |
| DCRV | 14 (9.0%) | 0 (0%) | 14 (11.4%) | 0.05 |
| PFO/ASD | 14 (9.0%) | 2 (6.3%) | 12 (9.8%) | 0.63 |
| Left SVC | 8 (5.2%) | 3 (9.4%) | 5 (4.1%) | 0.12 |
| Interrupted aortic arch | 8 (5.2%) | 3 (9.4%) | 5 (4.1%) | 0.13 |
| Mitral valve ring | 5 (3.2%) | 2 (6.3%) | 3 (2.4%) | 0.08 |
| Tetralogy of Fallot | 3 (1.9%) | 0 (0%) | 3 (2.4%) | 0.36 |
| Cor triatriatum | 1 (0.6%) | 0 (0%) | 1 (0.8%) | – |
| Pulmonary stenosis | 1 (0.6%) | 1 (3.1%) | 0 (0%) | – |
| Scimitar | 1 (0.6%) | 1 (3.1%) | 0 (0%) | – |
| Rhabdomyoma | 1 (0.6%) | 0 (0%) | 1 (0.8%) | – |
| Ebstein anomaly | 1 (0.6%) | 0 (0%) | 1 (0.8%) | – |
Values are given as median (range) or number (percent).
AoV, aortic valve; ASD, atrial septal defect; DCRV, double-chambered RV; DSS, discrete subaortic stenosis; FMR, fibromuscular ridge; MV, mitral valve; PFO, patent foramen ovale; SVC, superior vena cava; VSD, ventricular septal defect.