| Obese mice | Obese mice | IRKO mice | IRKO mice | |
|---|---|---|---|---|
| Wildtype | Transgenic | Wildtype | Transgenic | |
| Weight (g) | 45.0±1.2 | 42.4±1.0 | 25.5±1.8 | 26.4±0.6 |
| Systolic pressure (mm Hg) | 122±1.7 | 108±4.8* | 120±7.5 | 105±3.6* |
| NO-mediated vasorelaxation with insulin incubation(%) | 6±5.7 | 21±8.6* | 11±13.3 | 32±8.9* |
| Fasting glucose (mmol/l) | 7.9±0.4 | 6.7±0.3* | 5.1±0.5 | 4.9±0.4 |
| Peak glucose at GTT (mmol/l) | 17.4±0.7 | 14.0±0.4* | 9.8±0.2 | 9.5±0.2 |
| Trough glucose at ITT (mmol/l) | 5.3±0.3 | 4.3±0.3* |