Univariate analysis of factors associated with major cardiovascular events in 280 patients (missing data in 10/290 patients in regards to ethnicity)
| Factor | Univariate HR (95% CI) | Univariate p value |
|---|---|---|
| Mild RHD | 1 | <0.001 |
| Moderate RHD | 8.1 (2.8 to 23.3) | |
| Severe RHD | 24.9 (8.8 to 70.8) | |
| ARF vs no ARF | 0.17 (0.09 to 0.30) | <0.001 |
| Sex (male) | 0.8 (0.5 to 1.3) | 0.34 |
| Melanesian* | 0.6 (0.4 to 1.1) | 0.09 |
| Age group (years) | ||
| 5–20 | 1 | <0.001 |
| 21–40 | 6.1 (2.9 to 12.41) | |
| >40 | 15.2 (8.0 to 28.8) | |
| Ongoing secondary prophylaxis at FU* | 0.13 (0.07 to 0.23) | <0.001 |
*Analysis for 217 patients.
ARF, acute rheumatic fever; FU, follow-up; RHD, rheumatic heart disease.