Variable | Mean±SD | Median (25–75% IQR) | No of patients (%) |
Age (years) | 71±10 | 73 (64–79) | 187 |
Male gender | 143 (76.4) | ||
Caucasian/Native American | 185/2 | ||
NYHA | |||
Class III | 172 (92.0) | ||
Class IV | 15 (8.0) | ||
Duration of heart failure (months) | 41.9±44.2 | 31 (6–65) | 187 |
LVEF (%) | 27.3±12.2 | 24 (18–33) | 187 |
Weight (kg) | 87±23 | 82 (73–97) | 187 |
Height (cm) | 172±9 | 174 (166–178) | 187 |
BMI (kg/m2) | 29.2±6.7 | 28 (25–32.5) | 187 |
Heart rate (beats/min) | 71±13 | 71 (62–80) | 187 |
Systolic BP (mm Hg) | 113±21 | 110 (98–124) | 187 |
Diastolic BP (mm Hg) | 63±11 | 60 (58–70) | 187 |
Haemoglobin (g/dl) | 12.5±1.7 | 12.4 (11.1–13.7) | 99 |
Serum creatinine, mg/dL | 1.6±0.6 | 1.5 (1.3–1.9) | 187 |
GFR (ml/min/1.73 m2) | 46±15 | 45 (35–57) | 187 |
Potassium (mEq/l) | 4.4±0.9 | 4.4 (4.1–4.7) | 187 |
Sodium (mEq/l) | 139±4.1 | 140 (137–142) | 184 |
MR-proANP (pmol/l) | 395±304 | 333 (202–476) | 187 |
Copeptin (pmol/l) | 24.4±24.7 | 16.6 (7.3–31.1) | 187 |
BNP (pg/ml) | 408±423 | 305 (118–521) | 187 |
Troponin T (ng/ml) | 0.074±0.491 | 0.013 (0.005–0.035) | 187 |
Aetiology of HF | |||
Ischaemic | 101 (54.0) | ||
IDCM | 56 (29.9) | ||
Hypertension | 5 (2.6) | ||
Valvular | 7 (3.7) | ||
Other | 18 (9.6) | ||
Diabetes | 28 (15) | ||
Hypertension | 120 (64) | ||
Hyperlipidaemia | 121 (65) | ||
COPD | 49 (26) | ||
History of CABG | 82 (44) | ||
BiV pacemaker | 27 (14) | ||
AICD | 50 (27) | ||
History of MI | 91 (49) | ||
History of CVA | 12 (6) | ||
Never smoker | 68 (36) | ||
Atrial fibrillation | 86 (46) | ||
Aortic stenosis | 20 (11) | ||
Aortic regurgitation | 46 (24) | ||
Mitral regurgitation | 141 (75) | ||
Tricuspid regurgitation | 130 (70) | ||
History of valve replacement surgery | 17 (9) | ||
Drugs | |||
ACE1 | 140 (75) | ||
ARB | 34 (18) | ||
β-blocker | 147 (78) | ||
Aldosterone blocker | 50 (27) | ||
Digoxin | 113 (60) | ||
Diuretic | 173 (92) | ||
Aspirin | 114 (61) | ||
Nitrates | 55 (29) | ||
Antidysrhythmics | 40 (21) |
ACE1, angiotensin converting enzyme inhibitor; AICD, automatic implantable cardioverter defibrillator; ARB, angiotension receptor blocker; BiV, biventricular; BMI, body mass index; BNP, B-type natriuretic peptide; BP, blood pressure; COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular accident; GFR, glomerular filtration rate; IDCM, idiopathic dilated cardiomyopathy; LVEF, left ventricular ejection fraction; MI, myocardial infarction; MR-proANP, midregional proatrial natriuretic peptide; NYHA, New York Heart Association.