Baseline characteristics of included patients
| Variable | Derivation study (N=698) | Validation study (N=463) | p Value |
|---|---|---|---|
| Age in years, mean (SD) | 58.6 (14.3) | 64 (15) | |
| Men (%) | 429 (61.5) | 270 (58.3) | 0.303 |
| Previous angina (%) | 220 (31.5) | 186 (40.2) | 0.002 |
| Previous myocardial infarction (%) | 166 (23.8) | 139 (30.0) | 0.023 |
| Hypertension (%) | 341 (48.9) | 197 (42.5) | 0.037 |
| Hyperlipidaemia (%) | 337 (48.3) | 186 (40.2) | 0.008 |
| Diabetes mellitus (%) | 125 (17.9) | 80 (17.3) | 0.854 |
| Smoking (%) | 216 (30.9) | 96 (20.7) | <0.001 |
| Family history of coronary heart disease (%) | 337 (48.3) | 171 (36.9) | <0.001 |
| Previous coronary intervention (%) | 140 (20.1) | 102 (22.0) | 0.480 |
| Peripheral vascular disease (%) | 13 (1.9) | 15 (3.2) | 0.224 |
| Cerebrovascular disease (%) | 71 (10.2) | 30 (6.5) | 0.037 |
| Time from symptom onset | |||
| 0–3 h | 324 (46.4) | 212 (45.8) | 0.079 |
| 3–6 h | 166 (23.8) | 94 (20.3) | |
| 6–12 h | 148 (21.2) | 64 (13.8) | |
| >12 h | 60 (8.6) | 93 (20.1) | |