Efficacy outcomes through 30 months by Human Development Index classification
| Event | Human Development Index (2010) classification | p Value | ||
|---|---|---|---|---|
| Very high (n=3659) | High (n=3744) | Medium (n=1898) | ||
| Cardiovascular death, MI or stroke | <0.001 | |||
| No. of events | 599 | 452 | 209 | |
| Event rate at 30 months* | 23.1 (21.1 to 25.0) | 16.9 (15.1 to 18.7) | 17.6 (13.4 to 21.8) | |
| Cardiovascular death | 0.084 | |||
| No. of events | 270 | 231 | 134 | |
| Event rate at 30 months* | 11.3 (9.8 to 12.9) | 8.6 (7.3 to 10.0) | 10.1 (8.2 to 12.0) | |
| MI | <0.001 | |||
| No. of events | 382 | 270 | 79 | |
| Event rate at 30 months* | 14.7 (13.1 to 16.3) | 10.0 (8.6 to 11.4) | 8.5 (4.3 to 12.7) | |
| Stroke | 0.237 | |||
| No. of events | 61 | 47 | 22 | |
| Event rate at 30 months* | 2.6 (1.8 to 3.3) | 2.5 (1.5 to 3.5) | 1.6 (0.8 to 2.4) | |
| All-cause death | 0.069 | |||
| No. of events | 346 | 295 | 148 | |
| Event rate at 30 months* | 13.4 (11.9 to 15.0) | 10.7 (9.3 to 12.1) | 10.6 (8.7 to 12.5) | |
*Data presented as K-M rate at 30 months (95% CI).
MI, myocardial infarction.