Multivariate analysis of factors associated with major cardiovascular events in 280 patients (missing data in 10/290 patients in regards to ethnicity)
| Factor | Multivariate HR (95% CI) | Multivariate p value |
|---|---|---|
| Mild RHD | 1 | <0.001 |
| Moderate RHD | 3.36 (1.10 to 10.34) | |
| Severe RHD | 10.54 (3.50 to 31.75) | |
| ARF vs no ARF | 0.46 (0.24 to 0.89) | 0.02 |
| Sex (male) | 0.81 (0.48 to 1.36) | 0.43 |
| Melanesian | 0.66 (0.37 to 1.18) | 0.16 |
| Age group (years) | ||
| 5–20 | 1 | <0.001 |
| 21–40 | 2.88 (1.34 to 6.22) | |
| >40 | 5.15 (2.44 to 10.88) |
ARF, acute rheumatic fever; RHD, rheumatic heart disease.