SNP | Genotype | Additive | Dominant | Recessive | |||||
---|---|---|---|---|---|---|---|---|---|
C1236T | CC | CT | TT | Per T allele | CC | CT/TT | CC/CT | TT | |
N | 51 | 89 | 35 | 175 | 51 | 124 | 140 | 35 | |
Ref | 0.28 (0.07 to 0.48) | 0.39 (0.14 to 0.64) | 0.20 (0.08 to 0.33) | Ref | 0.31 (0.11 to 0.51) | Ref | 0.22 (−0.01 to 0.44) | ||
G2677T | GG | GT | TT | Per T allele | GG | GT/TT | GG/GT | TT | |
N | 50 | 92 | 33 | 175 | 50 | 125 | 142 | 33 | |
Ref | 0.29 (0.09 to 0.50) | 0.35 (0.09 to 0.61) | 0.19 (0.06 to 0.32) | Ref | 0.31 (0.11 to 0.51) | Ref | 0.16 (−0.07 to 0.39) | ||
C3435T | CC | CT | TT | Per T allele | CC | CT/TT | CC/CT | TT | |
N | 36 | 85 | 54 | 175 | 36 | 139 | 121 | 54 | |
Ref | 0.27 (0.04 to 0.50) | 0.27 (0.02 to 0.52) | 0.12 (0.00 to 0.24) | Ref | 0.27 (0.05 to 0.49) | Ref | 0.07 (−0.12 to 0.27) |
Adjusted for sex, age and digoxin dose.
Bold indicates statistically significant result (p<0.05).
ABCB1, ATP-binding cassette B1; SNPs, single-nucleotide polymorphisms.