Survival analysis of ischaemic heart disease
| No miscarriages N=49 579 | Non-consecutive miscarriage N=9419 | 2 Consecutive miscarriages N=940 | ≥3 Consecutive miscarriages N=167 | |
|---|---|---|---|---|
| Events, N (%) | 1440 (2.9) | 272 (2.9) | 30 (3.2) | 7 (4.2) |
| Person-years* | 1006 | 192 | 15 | 3 |
| Univariate HR (95% CI) | 1.0 | 0.92 (0.81 to 1.05) | 2.24 (1.56 to 3.22) | 4.00 (1.90 to 8.42) |
| Multivariate†‡ HR (95% CI) Missing§ (%) | 1.0 | 1.28 (0.96 to 1.72) (38.5) | 2.40 (1.28 to 4.51) (31.3) | 3.80 (0.94 to 15.33) (30.8) |
| Multivariate†¶ HR (95% CI) | 1.0 | 0.99 (0.87 to 1.13) | 1.75 (1.22 to 2.52) | 3.18 (1.49 to 6.80) |
*Person-years in thousands.
†Adjusted for maternal age, body mass index, social class and smoking.
‡Complete case analysis.
§Percentage of cases with missing covariates: exposed and unexposed groups together.
¶Multiple imputation model: model includes maternal age, body mass index, social class and smoking.