Changes in ambulatory heart rate range (AHRR) according to β-blocker titration
| β-blocker dose reduced (n=30) | β-blocker unchanged (n=119) | β-blocker increased (n=170) | p Value | |
|---|---|---|---|---|
| Change in bisoprolol dose (mg/day) | −3.8 (0.5) | 0 (0) | 4.1 (0.2) | <0.001 |
| Bisoprolol dose at follow-up (mg/day) | 0.9 (0.3) | 4.5 (0.3) | 6.4 (0.2) | <0.001 |
| Change in AHRR (bpm) | −2.8 (3.3) | −0.7 (1.5) | −5.1 (1.5) | 0.13 |
| AHRR at follow-up (bpm) | 42.5 (2.5) | 45.9 (1.5) | 46.5 (0.9) | 0.5 |