Crude incidence rates of 12 CVDs with 95% CIs in individuals with and without PMR and GCA
| Coronary and CVD death composite | Fatal and non-fatal cardiovascular composite | |||
|---|---|---|---|---|
| No. Events | Rate per 1000 PY (95% CI) | No. events | Rate per 1000 PY (95% CI) | |
| PMR only | 1075 | 23.95 (22.56 to 25.43) | 2457 | 54.74 (52.62 to 56.95) |
| GCA only | 148 | 30.44 (25.91 to 35.76) | 387 | 79.60 (72.05 to 87.94) |
| All GCA | 216 | 25.32 (22.16 to 28.93) | 555 | 65.06 (59.86 to 70.70) |
| PMR and/or GCA | 1291 | 24.17 (22.89 to 25.52) | 3012 | 56.39 (54.41 to 58.44) |
| Free of PMR and GCA | 10 826 | 25.80 (25.32 to 26.29) | 24 372 | 58.08 (57.36 to 58.82) |
Notes: non-disease estimates are obtained in up to 10 randomly selected patients without PMR or GCA matched for sex, age, medical practice and index date; PY rates are unadjusted; PMR and GCA estimates are obtained among patients diagnosed with these diseases who had supporting information for disease diagnosis. The coronary and CVD death composite endpoint includes: stable angina, myocardial infarction, coronary heart diseases not otherwise specified and any cardiovascular death. The fatal and non-fatal CVD composite endpoint additionally includes: transient ischaemic attack, peripheral arterial disease and non-fatal heart failure and ischaemic or haemorrhagic stroke.
CVD, cardiovascular disease; GCA, giant cell arteritis; PMR, polymyalgia rheumatica; PY, patient-years of follow-up.