Significant univariate Cox proportional survival analysis according to the main variables for the SCD end point
| HR | 95% CI | p Values | C index | |
|---|---|---|---|---|
| FH-SCD | 3.028 | 1.265 to 7.252 | 0.013 | 0.590 |
| NVST | 3.125 | 1.380 to 7.081 | 0.006 | 0.626 |
| ABPRE* | 2.327 | 1.003 to 5.399 | 0.049 | 0.576 |
| MWT >30 mm | 3.439 | 1.366 to 8.653 | 0.009 | 0.552 |
| LVEF, %*† | 0.935 | 0.892 to 0.979 | 0.004 | 0.625 |
| MWT, mm† | 1.095 | 1.020 to 1.175 | 0.012 | 0.564 |
| LAd, mm† | 1.059 | 1.007 to 1.113 | 0.026 | 0.663 |
| 2011 ACCF/AHA guidelines score | 4.826 | 2.082 to 11.190 | 0.000 | 0.665 |
| 2014 ESC guidelines score | 1.189 | 1.096 to 1.290 | 0.000 | 0.687 |
| ΔSBP, mm Hg | 0.981 | 0.964 to 0.998 | 0.028 | 0.618 |
| Peak HR, % of predicted*† | 0.967 | 0.958 to 0.982 | 0.000 | 0.612 |
| VO2AT, mL/kg/min | 0.822 | 0.719 to 0.939 | 0.004 | 0.697 |
| VO2AT, % of peak VO2 predicted | 0.956 | 0.925 to 0.996 | 0.031 | 0.646 |
| Peak VO2, mL/kg/min | 0.912 | 0.847 to 0.981 | 0.014 | 0.635 |
| Peak VO2, % of predicted*† | 0.962 | 0.934 to 0.986 | 0.002 | 0.647 |
| CP, mL/kg×mm Hg | 0.999 | 0.999 to 1.000 | 0.005 | 0.677 |
| CP%, % of predicted×mm Hg*† | 0.999 | 0.9997 to 0.9999 | 0.001 | 0.680 |
| VO2/WL slope, mL/min/W*† | 0.750 | 0.608 to 0.925 | 0.007 | 0.671 |
| VE/VCO2 slope*† | 1.081 | 1.038 to 1.125 | 0.000 | 0.691 |
*Variables included into the multivariate model including the 2014 ESC guidelines score (see table 4).
†Variables included into the multivariate model including the 2011 ACCF/AHA guidelines score (see table 4).
ABPRE, abnormal blood pressure response at exercise; ACCF, American College of Cardiology Foundation; AHA, American Heart Association; AT, anaerobic threshold; CP, circulatory power; FH, family history; HR, heart rate; ESC, European Society of Cardiology; LAd, left atrial diameter; LVEF, left ventricular ejection fraction; MWT, maximum wall thickness; NSVT, non sustained ventricular tachycardia; ΔSBP, difference between peak and resting systolic blood pressures; SCD, sudden cardiac death; VO2, oxygen consumption; VO2/WL slope, relation between VO2 versus work load; VE/VCO2 slope, relation between ventilation versus carbon dioxide production.