Table 1

Recommendations for supportive measures and pharmacotherapy in PPHN and PH associated with BPD/nCLD

Embedded Image

  • Recommendations relate to the grading system suggested by the European Society of Cardiology (ESC) and the American Heart Association (AHA), data derived from paediatric studies only (class, level of evidence).

  • BPD, bronchopulmonary dysplasia; CLD, chronic lung disease; nCLD, neonatal CLD; COR, class of recommendation; ECMO, extracorporal membrane oxygenation; iNO, inhaled nitric oxide; LOE, levels of evidence; PH, pulmonary hypertension; PPHN, persistent pulmonary hypertension of the newborn.