Unadjusted/adjusted HRs for the comparison between sinus rhythm (SR) and atrial fibrillation (AF) in patients with non-ST-elevation myocardial infarction (NSTEMI) and ST-elevation myocardial infarction (STEMI)
| Patients with NSTEMI | Patients with STEMI | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Outcome | Rhythm | Person-years | No. of events | Event rate/100 person-years (95% CI) | Unadjusted HR (95% CI) Adjusted HR (95% CI) | Person-years | No. of events | Event rate/100 person-years | Unadjusted HR (95% CI) Adjusted HR (95% CI) | Unadjusted Adjusted p value, interaction |
| Composite cardiovascular outcome | Sinus rhythm | 18 587.5 | 8194 | 44.1 (43.1 to 45.1) | 1.00 | 11 383.8 | 5366 | 47.1 (45.9 to 48.4) | 1.00 | – |
| Atrial fibrillation | 3577.9 | 3110 | 86.9 (83.9 to 90.0) | 1.93 (1.86 to 2.02) 1.24 (1.13 to 1.36) | 1579.1 | 1579 | 100.0 (95.2 to 105.0) | 2.07 (1.96 to 2.19) 1.34 (1.21 to 1.48) | 0.05 0.23 | |
| Mortality | Sinus rhythm | 19 534.0 | 2886 | 14.8 (14.2 to 15.3) | 1.00 | 12 024.1 | 1884 | 15.7 (15.0 to 16.4) | 1.00 | – |
| Atrial fibrillation | 3843.8 | 1597 | 41.6 (39.6 to 43.6) | 2.79 (2.62 to 2.96) 1.49 (1.27 to 1.75) | 1701.5 | 889 | 52.3 (48.9 to 55.8) | 3.30 (3.05 to 3.58) 1.72 (1.46 to 2.02) | <0.001 0.21 | |
| Myocardial infarction | Sinus rhythm | 18 648.0 | 6438 | 34.5 (33.7 to 35.4) | 1.00 | 11 421.3 | 4363 | 38.2 (37.1 to 39.4) | 1.00 | – |
| Atrial fibrillation | 3612.6 | 2067 | 57.2 (54.8 to 59.7) | 1.62 (1.55 to 1.71) 1.14 (1.02 to 1.26) | 1597.1 | 1030 | 64.5 (60.6 to 68.5) | 1.65 (1.55 to 1.77) 1.16 (1.03 to 1.30) | 0.67 0.78 | |
| Ischaemic stroke | Sinus rhythm | 19 452.4 | 717 | 3.7 (3.4 to 4.0) | 1.00 | 11 970.1 | 450 | 3.8 (3.4 to 4.1) | 1.00 | – |
| Atrial fibrillation | 3798.8 | 439 | 11.6 (10.5 to 12.7) | 3.11 (2.76 to 3.50) 2.19 (1.75 to 2.75) | 1678.1 | 235 | 14.0 (12.3 to 15.9) | 3.69 (3.15 to 4.32) 2.44 (1.88 to 3.17) | 0.09 0.52 | |